Angiotensine Converting Enzyme 1 (ACE) Mouse Monoclonal Antibody [Kloon ID: LBI2G5]

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]

Carrier-free (BSA/glycerol-free) ACE mouse monoclonal antibody, clone LBI2G5

ACE1; CD143; DCP; DCP1

Homo sapiens angiotensin I converting enzyme (ACE), transcript variant 1, mRNA.

1636

P12821

Unconjugated

Hypertrophic cardiomyopathy (HCM), Renin-angiotensin system

Hypertrophic cardiomyopathy (HCM), Renin-angiotensin system

WB 1:500, IHC 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

ACE

https://www.ncbi.nlm.nih.gov/gene/?term=1636

https://www.uniprot.org/uniprot/P12821