ANGPT1 Antilichaam

This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

284

Q15389

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 161-293 of human ANGPT1 (NP_001186788.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Growth Factors

Affinity purification

A-549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 54/57kDa

IgG

WB: 1:500 - 1:2000

ANGPT1

Mouse heart

Rat heart

Angiopoietin 1

Homo sapiens

ANGPT1, angiopoietin 1, ANG1, AGPT, AGP1, KIAA0003

WB

Liquid