ANKS1B Polyklonale Antilichaam, PE Vervoeging

The _-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer?s disease patients and AbPP intracellular domain (AID) . AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.

AIDA 1; AIDA-1; Amyloid-beta protein intracellular domain-associated protein 1; Anks1b; Ankyrin repeat and sterile alpha mot domain-containing protein 1B; ANS1B_HUMAN; E2A-PBX1-associated protein; EB-1.

56899

Q7Z6G8

Human, Mouse, Rat

851-1000/1248

ANKS1B

PE

KLH conjugated synthetic peptide derived from human ANKS1B/AIDA1

IF

Purified by Protein A.

496,564nm/578nm

1µg/µl

IF (IF=1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

56899