Anti-A2M/Alfa 2 Macroglobuline Konijn Monoklonale Antilichaam

Boster Bio Anti-A2M/Alpha 2 Macroglobulin Rabbit Monoclonal Antibody catalog # M01498. Tested in WB, IHC applications. This antibody reacts with Human.

Alpha-2-macroglobulin; Alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; A2M; CPAMD5; FWP007

A2M

2

P01023

Human

A synthesized peptide derived from human A2M

Clone: ABAO-1

Secreted in plasma. .

WB, IHC

Cell Biology, Complement, Immunology, Innate Immunity, Protease Inhibitors, Proteolysis/Ubiquitin

Affinity-chromatography

0.5mg/ml

Liquid

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced) . Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01498

163291 MW

60 kDa

Alpha-2-macroglobulin

Secreted .

Glycogen synthase kinase-3 beta (gsk3b)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.