Anti-ABCG2/Bcrp Konijn Monoklonale Antilichaam

Boster Bio Anti-ABCG2/Bcrp Rabbit Monoclonal Antibody catalog # M00457. Tested in WB application. This antibody reacts with Human.

ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; Urate exporter; CD338; ABCG2; ABCP, BCRP, BCRP1, MXR

ABCG2

9429

Q9UNQ0

Human

A synthesized peptide derived from human ABCG2

Clone: AODG-1

Highly expressed in placenta. Low expression in small intestine, liver and colon. .

WB

Signal Transduction, Stem Cells, Surface Molecules, Tags & Cell Markers, Tumor Associated

Affinity-chromatography

0.5mg/ml

Liquid

High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00457

72314 MW

73 kDa

ATP-binding cassette sub-family G member 2

Cell membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.

T-cell surface glycoprotein CD4

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.