Anti-ABHD4 Antibody Picoband® 31.0550 Vervoeging

Predicted to enable lysophosphatidic acid acyltransferase activity and lysophospholipase activity. Predicted to be involved in N-acylphosphatidylethanolamine metabolic process; lipid homeostasis; and phosphatidic acid biosynthetic process. Predicted to act upstream of or within N-acylethanolamine metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in lipid droplet and mitochondrion.

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

ABHD4

63874

Q8TB40

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human ABHD4 recombinant protein (Position: Q27-D342) .

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Flow Cytometry

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Immunogen affinity purified.

Liquid

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

1. Gross, M. B. Personal Communication. Baltimore, Md. 1/27/2022. 2. Laszlo, Z. I., Lele, Z., Zoldi, M., Miczan, V., Mogor, F., Simon, G. M., Mackie, K., Kacskovics, I., Cravatt, B. F., Katona, I. ABHD4-dependent developmental anoikis safeguards the embryonic brain. Nature Commun. 11: 4363, 2020. 3. Lee, H.-C., Simon, G. M., Cravatt, B. F. ABHD4 regulates multiple classes of N-acyl phospholipids in the mammalian central nervous system. Biochemistry 54: 2539-2549, 2015.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

64099 MW

6

RNA-binding protein 47

Nucleus .

Follicular dendritic cell secreted peptide

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.