Anti-Acetyl-NF-E4 (K43) Antilichaam

Boster Bio Anti-Acetyl-NF-E4 (K43) Antibody catalog # A14260. Tested in WB, ELISA, IHC applications. This antibody reacts with Human.

Transcription factor NF-E4; NFE4

NFE4

Q86UQ8

Human

Synthesized acetyl-peptide derived from the human NF-E4 around the acetylation site of K43.

Specifically expressed in fetal liver, cord blood and bone marrow. Also expressed in the K562 and HEL cell lines, which constitutively express the fetal globin genes. .

WB, ELISA, IHC

Immunogen affinity purified

>5000 cells

1 mg/mL

Liquid

Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR) . The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A14260

19019 MW

Transcription factor NF-E4

Nucleus .

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.