Anti-adiponectine/ADIPOQ Antilichaam Picoband® 31.0550 Vervoeging

Adiponectin, also known as APM1 or ACDC, is a protein which in humans is encoded by the ADIPOQ gene. It is mapped to chromosome 16 in a region showing homology of synteny with human 3q27. By RNase protection and Western blot analysis, it has been showed that Adiponectin is expressed by differentiated adipocytes as a 33-kD protein that is also detectable in serum. By sequence comparisons, it has been found that links between APM1 and TNF family ligands as well as to cytokines expressed by T cells. Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation. This gene is exclusively secreted from adipose tissue (and also from the placenta in pregnancy) into the bloodstream and is very abundant in plasma relative to many hormones.

30 kDa adipocyte complement-related protein ; Adiponectin, C1Q and collagen domain containing ; Protein Adipoq ; Adipoq ; Acdc ; rCG_36676

ADIPOQ

246253

Q8K3R4

Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived rat Adiponectin recombinant protein (Position: I19-N244) . Rat Adiponectin shares 90% amino acid (aa) sequence identity with mouse Adiponectin.

Flow Cytometry

Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Diabetes, Diabetes-associated, Growth Factors/Hormones, Heart Disease, Lipids/Lipoproteins, Mesenchymal Stem Cells, Metabolism, Metabolism Processes, Neurology Process, Neuroscience, Obesity, Pathways and Processes, Response To Hypoxia, Signal Transduction, Stem Cells

Immunogen affinity purified.

Liquid

1. Das, K., Lin, Y., Widen, E., Zhang, Y., Scherer, P. E. Chromosomal localization, expression pattern, and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30. Biochem. Biophys. Res. Commun. 280: 1120-1129, 2001. 2. Schaffler, A., Orso, E., Palitzsch, K.-D., Buchler, C., Drobnik, W., Furst, A., Scholmerich, J., Schmitz, G. The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidaemia (FCH) . Biochem. Biophys. Res. Commun. 260: 416-425, 1999.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

26410 MW

No cross reactivity with other proteins.

6

Adiponectin, C1Q and collagen domain containing

30 kDa adipocyte complement-related protein

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.