Anti-ALDH3A1 Antibody Picoband® fluoro488 Vervoeging

ALDH3A1 (Aldehyde Dehydrogenase, Family 3, Subfamily A, Member 1), also known as ALDH3, is an enzyme that in humans is encoded by the ALDH3A1 gene. By in situ hybridization, Hiraoka et al. (1995) mapped the ALDH3 gene to 17p11.2. ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.

Aldehyde dehydrogenase, dimeric NADP-preferring;1.2.1.5; ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1; ALDH3A1; ALDH3

ALDH3A1

218

P30838

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human ALDH3A1.

High levels in stomach, esophagus and lung; low level in the liver and kidney.

Flow Cytometry

Cancer, Cell Biology, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Neuroscience, Oxidative Stress, Pathways and Processes, Redox Metabolism, Sensory System, Signal Transduction, Visual System

Immunogen affinity purified.

Liquid

ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.

1. Hiraoka, L. R., Hsu, L., Hsieh, C.-L. Assignment of ALDH3 to human chromosome 17p11.2 and ALDH5 to human chromosome 9p13. Genomics 25: 323-325, 1995. 2. Santisteban, I., Povey, S., West, L. F., Parrington, J. M., Hopkinson, D. A. Chromosome assignment, biochemical and immunological studies on a human aldehyde dehydrogenase, ALDH3. Ann. Hum. Genet. 49: 87-100, 1985.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

50395 MW

No cross reactivity with other proteins.

6

Aldehyde dehydrogenase, dimeric NADP-preferring

Cytoplasm.

Belongs to the aldehyde dehydrogenase family.

Aldehyde dehydrogenase, dimeric NADP-preferring

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.