Anti-alfa 1 Spectrin Rabbit Monoklonale Antilichaam

Boster Bio Anti-alpha 1 Spectrin Rabbit Monoclonal Antibody catalog # M03376-1. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Calnexin; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90; CANX

SPTA1

6708

P02549

Human, Mouse, Rat

A synthesized peptide derived from human alpha 1 Spectrin

Clone: 23S53

Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine. .

WB, ICC, IF, Flow Cytometry

Actin Binding Proteins, Actin, etc., Cardiovascular, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M03376-1

67568 MW

280 kDa

Calnexin

Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065) . The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232) . .

T-cell surface glycoprotein CD3 zeta chain

IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.