Anti-AMPK beta 1 PRKAB1 Konijn Monoklonale Antilichaam

Boster Bio Anti-AMPK beta 1 PRKAB1 Rabbit Monoclonal Antibody catalog # M03741. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

5'-AMP-activated protein kinase subunit beta-1; AMPK subunit beta-1; AMPKb; PRKAB1; AMPK

PRKAB1

5564

Q9Y478

Human, Mouse, Rat

A synthesized peptide derived from human AMPK beta 1

Clone: HFH-16

Expressed in the terminally differentiated epidermis of palms and soles. .

WB, Flow Cytometry

Cancer, Cancer Metabolism, Cardiovascular, Energy Transfer Pathways, Fatty Acid Oxidation, Fatty Acids, Integration Of Energy, Integration Of Energy Metabolism, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipid Signaling, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Redox Metabolism, Signal Transduction, Signaling Pathway

Affinity-chromatography

0.5mg/ml

Liquid

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by inly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3) .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M03741

30382 MW

28 kDa

5'-AMP-activated protein kinase subunit beta-1

Cytoplasm, myofibril, sarcomere, Z line . Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.