Anti-amyloïde bètapeptide (A-beta 40/42) Antilichaam

Our Anti-Amyloid beta peptide (A-beta 40/42) mouse monoclonal primary antibody detects human and rat Amyloid beta peptide (A-beta 40/42), and is igg. It is validated for use in ELISA, FC, ICC, IHC-Frozen, IHC-Paraffin-embedded, IP, WB.

Our Anti-Amyloid beta peptide (A-beta 40/42) mouse monoclonal primary antibody detects human and rat Amyloid beta peptide (A-beta 40/42), and is IgG. It is validated for use in ELISA, FC, ICC, IHC-Frozen, IHC-Paraffin-embedded, IP, WB.

Beta-APP42; Beta-APP40; Beta-amyloid protein 42; Beta-amyloid protein 40; ABPP; APPI; Amyloid beta A4 protein; MOAB2; MOAB-2; Alzheimer's antibody; AB40; AB42; abeta

P05067

Human and Rat

Recombinant human amyloid beta protein 42 (Aβ42) : DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

Amyloid beta peptide (A-beta 40/42)

MOAB-2

Unconjugated

ELISA, FC, ICC, IHC-Frozen, IHC-Paraffin-embedded, IP, WB

MOAB-2_extended product_information_M-1586-100_M-1752-50_2024.pdf MOAB-2_extended product_information_M-1586-100_M-1752-50_2024.pdf

IgG

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Final buffer is 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, 0.01% sodium azide, 0.1% trehalose, pH 7.2.After reconstitution keep aliquots at -20°C to -70°C for a higher stability. At 2-8°C keep up to one week, insulated, protected from light; use sterile methods and pipettes. Highly purified glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles. Keep tightly closed when not in use and protected from light.

This product is a Protein A purified mouse IgG2b in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, 0.01% sodium azide, pH 7.2.

1:50-1:1000

1:2000-1:5000

1:200-1:1000

MOAB-2 detects preparations enriched in U-, O-, F-Aβ42, and U-Aβ40 by dot-blot, and is thus a pan-specific Aβ antibody. However, MOAB-2 is selective for the more neurotoxic Aβ42 compared to Aβ40. Indeed, MOAB-2 demonstrated a titration against antigen concentration, and detects Aβ40 at 2.5 pmol but U-, O- and FAβb42 at antigen concentrations as low as ~ 0.1 pmol {Youmans. KL et al 2012}. MOAB-2 does not detect APP (Amyloid precursor protein) . Human, rat, other species not yet tested.By Dot blot, MOAB-2 detected rat Aβ40 and human Aβ40, albeit with less affinity than for Aβ42. {Youmans. KL et al 2012}.

Mouse

Lyophilized

IgG2b, lambda

Human