Anti-Androgen Receptor (AR-V7 specifiek) Konijn Monoklonale Antilichaam

Boster Bio Anti-Androgen Receptor (AR-V7 specific) Rabbit Monoclonal Antibody catalog # M00542-3. Tested in WB, IHC applications. This antibody reacts with Human.

Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR, NR3C4

AR

367

C0JKD3

Human

A synthesized peptide derived from human Androgen Receptor (AR-V7 specific)

Clone: DHH-1

Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333) . Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107) . .

WB, IHC

Cancer, Developmental Biology, Epigenetics and Nuclear Signaling, Nuclear Hormone Receptors, Nuclear Receptors, Nuclear Signaling, Nuclear Signaling Pathways, Reproduction, Signal Transduction, Signaling Pathway

Affinity-chromatography

0.5mg/ml

Liquid

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00542-3

99188 MW

54 kDa

Androgen receptor

Nucleus . Cytoplasm . Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1. .

T-cell surface glycoprotein CD4

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.