Anti-APOBEC3C Antibody Picoband® fluoro488 Vervoeging

DNA dC->dU-editing enzyme APOBEC-3C is a protein that in humans is encoded by the APOBEC3C gene. This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.

APOBEC3C; APOBEC1L; PBI; DNA dC->dU-editing enzyme APOBEC-3C; A3C; EC 3.5.4.38; APOBEC1-like; Phorbolin I

APOBEC3C

27350

Q9NRW3

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the N-terminus of human APOBEC3C.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Harris, R. S., Petersen-Mahrt, S. K., Neuberger, M. S. RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators. Molec. Cell 10: 1247-1253, 2002. 2. Jarmuz, A., Chester, A., Bayliss, J., Gisbourne, J., Dunham, I., Scott, J., Navaratnam, N. An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Genomics 79: 285-296, 2002. 3. Stauch, B., Hofmann, H., Perkovic, M., Weisel, M., Kopietz, F., Cichutek, K., Munk, C., Schneider, G. Model structure of APOBEC3C reveals a binding pocket modulating ribonucleic acid interaction required for encapsidation. Proc. Nat. Acad. Sci. 106: 12079-12084, 2009.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

23 kDa

6

Apolipoprotein B mRNA editing enzyme catalytic subunit 3C

DNA dC->dU-editing enzyme APOBEC-3C

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.