Anti-Apolipoproteïne D/APOD Antibody Picoband® fluoro647 Vervoeging

Apolipoprotein D (Apo-D) is a protein that in humans, encoded by the APOD gene. Being a member of the alpha (2 mu) -microglobulin superfamily of carrier proteins, Apo-D is also known as lipocalin.The gene has been localized to the p14.2----qter region of human chromosome 3. It is a glycoprotein of estimated molecular weight 33,000 Da. The Apo-D encoded a protein of 169 amino acid residue.It has been detected in human liver, intestine, pancreas, kidney, placenta, adrenal, spleen, and fetal brain tissue. For its features, Apo-D has been a biomarker of androgen insensitivity syndrome (AIS) .

Apolipoprotein D; Apo-D; ApoD; APOD

APOD

347

P05090

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human Apolipoprotein D.

Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.

Flow Cytometry

Growth Factors/Hormones, Signal Transduction

Immunogen affinity purified.

Liquid

APOD occurs in the macromolecular complex with lecithin- cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.

1. Drayna, D. T., McLean, J. W., Wion, K. L., Trent, J. M., Drabkin, H. A., Lawn, R. M. Human apolipoprotein D gene: gene sequence, chromosome localization, and homology to the alpha-2mu-globulin superfamily. DNA 6: 199-204, 1987. 2. Drayna, D., Fielding, C., McLean, J., Baer, B., Castro, G., Chen, E., Comstock, L., Henzel, W., Kohr, W., Rhee, L., Wion, K., Lawn, R.Cloning and expression of human apolipoprotein D cDNA.J. Biol. Chem.261: 16535-16539, 1986. 3. Appari M, Werner R, Wünsch L, Cario G, Demeter J, Hiort O, Riepe F, Brooks JD, Holterhus PM (June 2009) . Apolipoprotein D (APOD) is a putative biomarker of androgen receptor function in androgen insensitivity syndrome. J. Mol. Med. 87 (6) : 623–32.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

21276 MW

No cross reactivity with other proteins.

6

Apolipoprotein D

Secreted.

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Apolipoprotein D (Apo-D/ApoD)

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.