Anti-Aquaporine 9/AQP9 Antibody Picoband® 31.0647 Vervoeging

Aquaporin-9 is a protein that in humans is encoded by the AQP9 gene. AQP9 encodes a 295-amino-acid protein with the amino acid sequence identity with AQP3 (48%), AQP7 (45%), and other aquaporins (approximately 30%), suggesting that AQP3, AQP7, and AQP9 belong to a subfamily of the aquaporin family. AQP9 is the major glycerol channel in mouse erythrocytes and suggest that this transport pathway may contribute to the virulence of intraerythrocytic stages of malarial infection.

Aquaporin-9; AQP-9; Aquaglyceroporin-9; Aqp9

AQP9

64008

Q9JJJ3

Mouse

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 9.

Flow Cytometry

Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction

Immunogen affinity purified.

Liquid

Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na (+), K (+), Cl (-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol (By similarity) . .

1. Entrez Gene: AQP9 aquaporin 9 2. Ishibashi, K., Kuwahara, M., Gu, Y., Tanaka, Y., Marumo, F., Sasaki, S. Cloning and functional expression of a new aquaporin (AQP9) abundantly expressed in the peripheral leukocytes permeable to water and urea, but not to glycerol. Biochem. Biophys. Res. Commun. 244: 268-274, 1998. 3. Liu, Y., Promeneur, D., Rojek, A., Kumar, N., Frokiaer, J., Nielsen, S., King, L. S., Agre, P., Carbrey, J. M. Aquaporin 9 is the major pathway for glycerol uptake by mouse erythrocytes, with implications for malarial virulence. Proc. Nat. Acad. Sci. 104: 12560-12564, 2007.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

31764 MW

No cross reactivity with other proteins.

6

Aquaporin-9

Membrane ; Multi-pass membrane protein .

Aquaporin-9

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.