Anti-ARF6 Konijn Monoklonale Antilichaam

Boster Bio Anti-ARF6 Rabbit Monoclonal Antibody catalog # M00927. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

ADP-ribosylation factor 6; ARF6

ARF6

382

P62330

Human, Mouse, Rat

A synthesized peptide derived from human ARF6

Clone: AOFF-1

Ubiquitous, with higher levels in heart, substantia nigra, and kidney. .

WB, ICC, IF

Protein Trafficking, Signal Transduction, Vesicle Transport

Affinity-chromatography

0.5mg/ml

Liquid

GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00927

20082 MW

120-150 kDa

ADP-ribosylation factor 6

Golgi apparatus. Cell membrane; Lipid- anchor. Endosome membrane; Lipid-anchor. Recycling endosome membrane ; Lipid-anchor . Cell projection, filopodium membrane; Lipid-anchor. Midbody . Cytoplasm . Cleavage furrow . Distributed throughout the cytoplasm during metaphase. Transiently detected at the ingressing cleavage furrow during mitotic cytokinesis. Recruited to the midbody at later stages of cytokinesis; this requires interaction with KIF23 (By similarity) . Recruited to the cell membrane in association with CYTH2 and ARL4C. Colocalizes with DAB2IP at the plasma membrane and endocytic vesicles. .

Glycogen synthase kinase-3 beta (gsk3b)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.