Anti-ARHGAP18 Antilichaam

Boster Bio Anti-ARHGAP18 Antibody catalog # A08418. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Rho GTPase-activating protein 18; MacGAP ; Rho-type GTPase-activating protein 18; ARHGAP18

ARHGAP18

Q8N392

Human, Mouse

The antiserum was produced against synthesized peptide derived from human RHG18. AA range:517-566

WB, IHC, IF, ELISA

Immunogen affinity purified

1 mg/mL

Liquid

Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595) . Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702) . Regulates cell shape, spreading, and migration (PubMed:21865595) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A08418

74977 MW

Rho GTPase-activating protein 18

Cytoplasm .

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.