Anti-ASC-1 (G105) TRIP4 Antilichaam

Boster Bio Anti-ASC-1 (G105) TRIP4 Antibody catalog # A07762. Tested in IHC, IF applications. This antibody reacts with Human, Mouse.

Activating signal cointegrator 1

TRIP4

Q15650

Human, Mouse

Synthetic peptide, corresponding to amino acids 72-124 of Human ASC-1.

IHC, IF

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498) . Also involved in androgen receptor transactivation (By similarity) . Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF- kappa-B (PubMed:12077347) . May play a role in the development of neuromuscular junction (PubMed:26924529) . May play a role in late myogenic differentiation (By similarity) .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A07762

66146 MW

Activating signal cointegrator 1

Nucleus

Activating signal cointegrator 1

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2