Anti-Asparagine synthetase/ASNS Antibody Picoband® fluoro488 Vervoeging

The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene.

Glutathione S-transferase Mu 3; GST class-mu 3; GSTM3-3; hGSTM3-3; GSTM3; GST5

ASNS

440

P08243

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human Asparagine synthetase/ASNS recombinant protein (Position: M1-D531) .

Testis and brain.

Flow Cytometry

Cancer, Drug Metabolism, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction

Immunogen affinity purified.

Liquid

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers.

1. Abhyankar, A., Lamendola-Essel, M., Brennan, K., Giordano, J. L., Esteves, C., Felice, V., Wapner, R., Jobanputra, V. Clinical whole exome sequencing from dried blood spot identifies novel genetic defect underlying asparagine synthetase deficiency. Clin. Case Rep. 6: 200-205, 2018. 2. Arfin, S. M., Cirullo, R. E., Arredondo-Vega, F. X., Smith, M. Assignment of the structural gene for asparagine synthetase to human chromosome 7. Somat. Cell Genet. 9: 517-531, 1983. 3. Greco, A., Ittmann, M., Barletta, C., Basilico, C., Croce, C. M., Cannizzaro, L. A., Huebner, K. Chromosomal localization of human genes required for G (1) progression in mammalian cells. Genomics 4: 240-245, 1989.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Glutathione S-transferase mu 3

Cytoplasm.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.