Anti-ATF5 Antibody Picoband® 31.0550 Vervoeging

Activating transcription factor 5, also known as ATF5, is a protein that, in humans, is encoded by the ATF5 gene. Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and tubulin binding activity. Involved in several processes, including fat cell differentiation; regulation of cell cycle process; and regulation of transcription, DNA-templated. Located in centrosome; cytosol; and nucleoplasm.

ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx

ATF5

22809

Q9Y2D1

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human ATF5 recombinant protein (Position: L11-R275) . Human ATF5 shares 86.5% and 87.2% amino acid (aa) sequence identity with mouse and rat ATF5, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Pati, D., Meistrich, M. L., Plon, S. E. Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis. Molec. Cell. Biol. 19: 5001-5013, 1999. 2. Peters, C. S., Liang, X., Li, S., Kannan, S., Peng, Y., Taub, R., Diamond, R. H. ATF-7, a novel bZIP protein, interacts with the PRL-1 protein-tyrosine phosphatase. J. Biol. Chem. 276: 13718-13726, 2001. 3. Sheng, Z., Li, L., Zhu, L. J., Smith, T. W., Demers, A., Ross, A. H., Moser, R. P., Green, M. R. A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications. Nature Med. 16: 671-677, 2010.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

31 kDa

6

Activating transcription factor 5

Cyclic AMP-dependent transcription factor ATF-5

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.