Anti-ATOH1 Konijn Monoklonale Antilichaam

Boster Bio Anti-ATOH1 Rabbit Monoclonal Antibody catalog # M02207. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Caspase-10; CASP-10;3.4.22.63; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4; Caspase-10 subunit p23/17; Caspase-10 subunit p12; CASP10; MCH4

ATOH1

474

Q92858

Human, Mouse, Rat

A synthesized peptide derived from human MATH1/HATH1

Clone: 20A04

Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.

WB

Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Neuroscience, Sensory System, Transcription, Transcription Factors, Visual System

Affinity-chromatography

0.5mg/ml

Liquid

Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02207

58951 MW

68 kDa

Caspase-10

Cytoplasm. Nucleus. Cell membrane. Membrane, clathrin-coated pit . Cell projection, pseudopodium . Cytoplasmic vesicle. Translocates to the plasma membrane and colocalizes with antagonist-stimulated GPCRs. The monomeric form is predominantly located in the nucleus. The oligomeric form is located in the cytoplasm. Translocates to the nucleus upon stimulation of OPRD1 (By similarity) . .

Lysosome-associated membrane glycoprotein 2 (Lamp2)

IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.