Anti-ATP4B Antibody Picoband® 31.0647 Vervoeging

This gene encodes the beta subunit of the gastric H+, K+-ATPase. The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H (+) and K (+) ions across the plasma membrane. It is also responsible for gastric acid secretion.

ATP4B

496

P51164

Human, Mouse, Rat

E.coli-derived human ATP4B recombinant protein (Position: Y60-D277) . Human ATP4B shares 82.8% and 80.5% amino acid (aa) sequence identity with mouse and rat ATP4B, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Canfield, V. A., Okamoto, C. T., Chow, D., Dorfman, J., Gros, P., Forte, J. G., Levenson, R. Cloning of the H, K-ATPase beta subunit: tissue-specific expression, chromosomal assignment, and relationship to Na, K-ATPase beta subunits. J. Biol. Chem. 265: 19878-19884, 1990. 2. Reuben, M. A., Lasater, L. S., Sachs, G. Characterization of a beta subunit of the gastric H (+) /K (+) -transporting ATPase. Proc. Nat. Acad. Sci. 87: 6767-6771, 1990. 3. Song, I., Brown, D. R., Yamada, T., Trent, J. M. Mapping of the gene encoding the beta-subunit of H (+), K (+) -ATPase to human chromosome 13q34 by fluorescence in situ hybridization. Genomics 14: 1114-1115, 1992.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.