Anti-B7H6/NCR3LG1 Antilichaam Picoband® APC-vervoeging

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity.

NCR3LG1; B7H6; Natural cytotoxicity triggering receptor 3 ligand 1; B7 homolog 6; B7-H6

NCR3LG1

374383

Q68D85

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human B7H6/NCR3LG1 recombinant protein (Position: H85-D386) .

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Brandt, C. S., Baratin, M., Yi, E. C., Kennedy, J., Gao, Z., Fox, B., Haldeman, B., Ostrander, C. D., Kaifu, T., Chabannon, C., Moretta, A., West, R., Xu, W., Vivier, E., Levin, S. D. The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J. Exp. Med. 206: 1495-1503, 2009. 2. Li, Y., Wang, Q., Mariuzza, R. A. Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6. J. Exp. Med. 208: 703-714, 2011.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

51 kDa

6

Natural killer cell cytotoxicity receptor 3 ligand 1

Natural cytotoxicity triggering receptor 3 ligand 1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.