Anti-BAMBI Antilichaam

BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development (1) . BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4 (2,3) . BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues (4) . BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines (5) .

Boster Bio Anti-BAMBI Antibody (Catalog # A07983) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

BMP and activin membrane-bound inhibitor homolog

BAMBI

Q13145

Human, Mouse, Rat

BAMBI antibody is human, mouse and rat reactive.

BAMBI antibody was raised against a 17 amino acid peptide near the center of human BAMBI. The immunogen is located within amino acids 100 - 150 of BAMBI.

High expression in kidney medulla, placenta and spleen; low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested.

ELISA, WB, IHC-P, IF

Signal Transduction, Stem Cells

BAMBI antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Negatively regulates TGF-beta signaling.

BAMBI antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

https://www.bosterbio.com/msds?sku=A07983

29108 MW

BMP and activin membrane-bound inhibitor

Membrane ; Single-pass type I membrane protein .

Sheep

BMP and activin membrane-bound inhibitor

IgG

BAMBI antibody is supplied in PBS containing 0.02% sodium azide.