Anti-BCAT2 Antibody Picoband® 31.0647 Vervoeging

BCAT2, branched-chain aminotransferase 2, encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. The human BCAT2 gene is mapped to 19q13.

Branched-chain-amino-acid aminotransferase, mitochondrial; BCAT (m) ;2.6.1.42; Placental protein 18; PP18; BCAT2; BCATM, BCT2, ECA40

BCAT2

587

O15382

Human, Monkey

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human BCAT2.

Ubiquitous.

Flow Cytometry

Amino Acid Metabolism, Amino Acids, Cancer, Metabolic Signaling Pathways, Metabolism, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction

Immunogen affinity purified.

Liquid

Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.

1. Yennawar NH, et al. Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis. J Biol Chem, 2006 Dec 22. 2. Goto M, et al. Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. J Biol Chem, 2005 Nov 4.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

44288 MW

No cross reactivity with other proteins.

6

Branched-chain-amino-acid aminotransferase, mitochondrial

Isoform A: Mitochondrion.

Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT (m) )

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.