Anti-BCKDK Antibody Picoband®

Branched chain ketoacid dehydrogenase kinase (BCKDK) is an enzyme encoded by the BCKDK gene on chromosome 16. The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene.

Boster Bio Anti-BCKDK Antibody Picoband® catalog # A07798-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Protein SOX-15; Protein SOX-12; Protein SOX-20; SOX15; SOX12; SOX20; SOX26; SOX27

BCKDK

10295

O14874

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human BCKDK recombinant protein (Position: D36-R316) .

Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Binds to the 5'-AACAAT-3' sequence.

1. Doering, C. B., Coursey, C., Spangler, W., Danner, D. J. Murine branched chain alpha-ketoacid dehydrogenase kinase; cDNA cloning, tissue distribution, and temporal expression during embryonic development. Gene 212: 213-219, 1998. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 11/1/2012. 3. Joshi, M. A., Jeoung, N. H., Obayashi, M., Hattab, E. M., Brocken, E. G., Liechty, E. A., Kubek, M. J., Vattem, K. M., Wek, R. C., Harris, R. A. Impaired growth and neurological abnormalities in branched-chain alpha-keto acid dehydrogenase kinase-deficient mice. Biochem. J. 400: 153-162, 2006.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A07798-2

49229 MW

46 kDa

6

SRY-box 15

Nucleus.

Chromaffin granule amine transporter

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.