Anti-Bcl-2 Monoklonale antilichamen (kloon: Bcl-2-100)

Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t (14;18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene. Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line.

Apoptosis regulator Bcl-2; Bcl2; Bcl-2

Bcl2

24224

P49950

Human

Synthetic peptide corresponding to residues 41-54 of the bcl-2 protein, conjugated to thyroglobulin.

Apoptosis regulator Bcl-2

Bcl-2-100

WB, IHC-P, IHC-F, ICC

Ascites

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Western blot : 1-2μg/ml; Immunohistochemistry (Paraffin-embedded Section) : 0.4-1μg/ml; Immunohistochemistry (Frozen Section) : 0.4-1μg/ml; Immunocytochemistry : 1μg/ml

Mouse IgG1