Anti-beta Defensin 1/DEFB1 Antibody Picoband® fluoro594 Vervoeging

DEFB1, Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.

Beta-defensin 1; BD-1; hBD-1; Defensin, beta 1; DEFB1; BD1, HBD1

DEFB1

1672

P60022

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1.

Plasma.

Flow Cytometry

Cell Biology

Immunogen affinity purified.

Liquid

Has bactericidal activity. .

1. Jia, H. P., Starner, T., Ackermann, M., Kirby, P., Tack, B. F., McCray, P. B., Jr.Abundant human beta-defensin-1 expression in milk and mammary gland epithelium.J. 2. Liu, L., Zhao, C., Heng, H. H. Q., Ganz, T.The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry. 3. Valore, E. V., Park, C. H., Quayle, A. J., Wiles, K. R., McCray, P. B., Jr., Ganz, T.Human beta-defensin-1: an antimicrobial peptide of urogenital tissues.J. Clin.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

7420 MW

No cross reactivity with other proteins.

6

Beta-defensin 1

Secreted.

Belongs to the beta-defensin family.

Beta-defensin 1 (BD-1/hBD-1)

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.