Anti-Beta-HCG CGB Antilichaam (Monoklonal, PC-2)

Beta-HCG (beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain (CGB) . It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, beta-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. beta-HCG is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.

Boster Bio Anti-Beta-HCG CGB Antibody (Monoclonal, PC-2) catalog # MA1111. Tested in IHC applications. This antibody reacts with Human.

Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotrophin chain beta; CGB; CGB3; CGB5; CGB7; CGB8

CGB

Human (1082)

P01233

Human

Cross-reactivities with LH, FSH and TSH are less than 0.3%.

Purified human Chorionic Gonadotropin.

Clone: PC-2

Placenta.

IHC

Chromatin Remodeling, Co-Factors, Epigenetics and Nuclear Signaling, Transcription

Ascites

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Lyophilized

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

1. Bo, M.; Boime, I. : Identification of the transcriptionally active genes of the chorionic gonadotropin beta gene cluster in vivo. J. Biol. Chem. 267: 3179-3184, 1992.) 2. Policastro, P.; Ovitt, C. E.; Hoshina, M.; Fukuoka, H.; Boothby, M. R.; Biome, I. : The beta-subunit of human chorionic gonadotropin is encoded by multiple genes. J. Biol. Chem. 258: 11492-11499, 1983. 3. Zygmunt, M.; Herr, F.; Keller-Schoenwetter, S.; Kunzi-Rapp, K.; Munstedt, K.; Rao, C. V.; Lang, U.; Preissner, K. T. : Characterization of human chorionic gonadotropin as a novel angiogenic factor. J. Clin. Endocr. Metab. 87: 5290-5296, 2002.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=MA1111

17739 MW

55 kDa

No cross reactivity with other proteins.

Choriogonadotropin subunit beta

Secreted.

Belongs to the glycoprotein hormones subunit beta family.

Choriogonadotropin subunit beta

Mouse IgG1

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.