Anti-beta-HSD7 HSD3B7 Antilichaam

Boster Bio Anti-beta-HSD7 HSD3B7 Antibody catalog # A10025. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

3 beta-hydroxysteroid dehydrogenase type 7;3 beta-hydroxysteroid dehydrogenase type VII;3-beta-HSD VII;3-beta-hydroxy-Delta (5) -C27 steroid oxidoreductase; C (27) 3-beta-HSD;1.1.1.-; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase;1.1.1.181; HSD3B7

HSD3B7

Q9H2F3

Human, Mouse, Rat

The antiserum was produced against synthesized peptide derived from human HSD3B7. AA range:121-170

WB, ELISA

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/mL

Liquid

The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C (19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870) . Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7- alpha,25-OHC) : 7-alpha,25-OHC acts as a ligand for the G protein- coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A10025

41016 MW

3 beta-hydroxysteroid dehydrogenase type 7

Endoplasmic reticulum membrane; Multi-pass membrane protein.

3 beta-hydroxysteroid dehydrogenase type 7

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.