Anti-Beta-Synuclein Antilichaam

Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA) -stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease (Ref: uniprot.org) .

Our Anti-Beta-synuclein (β-synuclein, SNCB) mouse monoclonal primary antibody detects bovine, human, mouse, pig, and rat Beta-synuclein (β-synuclein, SNCB), and is affinity-purified. It is validated for use in IHC-Frozen, WB.

Our Anti-Beta-synuclein (β-synuclein, SNCB) mouse monoclonal primary antibody detects bovine, human, mouse, pig, and rat Beta-synuclein (β-synuclein, SNCB), and is affinity-purified. It is validated for use in IHC-Frozen, WB.

Beta-synuclein, β-synuclein

Q16143

Bovine, Human, Mouse, Pig, and Rat

C-terminal peptide of human β-synuclein (EPEGESYEDPPQEEYQEYEPEA) coupled to KLH.

Beta-synuclein (β-synuclein, SNCB)

6A10

Unconjugated

IHC-Frozen, WB

Affinity-purified

Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at -20°C for long-term storage. Store at 2-8°C short-term (up to 4 weeks) . Avoid repetitive freeze/thaw cycles.

Protein G purified

1:500-1:1000

0.7361111111111112

Validated by Western blotting and immunohistochemical procedures. Specific for β-synuclein, does not cross-react with α- or γ-synuclein.

Mouse

Lyophilized

IgG1

Human