Anti-Beta-Synuclein Antilichaam

Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA) -stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease (Ref: uniprot.org) .

Our Anti-Beta-synuclein (β-synuclein, SNCB) rabbit polyclonal primary antibody detects human, mouse, and rat Beta-synuclein (β-synuclein, SNCB), and is affinity-purified. It is validated for use in IHC-Frozen, WB.

Our Anti-Beta-synuclein (β-synuclein, SNCB) rabbit polyclonal primary antibody detects human, mouse, and rat Beta-synuclein (β-synuclein, SNCB), and is affinity-purified. It is validated for use in IHC-Frozen, WB.

Beta-synuclein, β-synuclein

Q16143

Human, Mouse, and Rat

Full-length human recombinant β-synuclein protein expressed in and purified from E. Coli.

Beta-synuclein (β-synuclein, SNCB)

Unconjugated

IHC-Frozen, WB

Affinity-purified

Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at -20°C for long-term storage. Store at 2-8°C short-term (up to 4 weeks) . Avoid repetitive freeze/thaw cycles.

1:1000-1:2000

1:1000-1:2000

Validated by Western blotting and immunohistochemical procedures. Specific for β-synuclein, does not cross-react with α- or γ-synuclein.

Rabbit

Lyophilized

IgG

Human