Anti-BHMT Antibody Picoband® fluoro488 Vervoeging

This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst (e) inemia, but such a defect has not yet been observed.

Neurocan core protein; Chondroitin sulfate proteoglycan 3; NCAN; CSPG3, NEUR

BHMT

635

Q93088

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human BHMT recombinant protein (Position: I13-K386) .

Brain.

Flow Cytometry

Cell Adhesion Proteins, ECM Proteins, Neuroscience

Immunogen affinity purified.

Liquid

May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM) . Chondroitin sulfate proteoglycan; binds to hyaluronic acid.

1. Garrow, T. A. Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase. J. Biol. Chem. 271: 22831-22838, 1996. 2. Li, F., Feng, Q., Lee, C., Wang, S., Pelleymounter, L. L., Moon, I., Eckloff, B. W., Wieben, E. D., Schaid, D. J., Yee, V., Weinshilboum, R. M. Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization. Molec. Genet. Metab. 94: 326-335, 2008. 3. Park, E. I., Garrow, T. A. Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene. J. Biol. Chem. 274: 7816-7824, 1999.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

104553 MW

6

Neurocan

Secreted .

AP-2 complex subunit beta

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.