Anti-Brain-afgeleide neurotrofe factor (BDNF) Antilichaam

BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG) . SIMILARITY: Belongs to the NGF-beta family.

Our Anti-Brain-derived neurotrophic factor (BDNF) chicken polyclonal primary antibody detects human and mouse Brain-derived neurotrophic factor (BDNF), and is igy. It is validated for use in ELISA.

Our Anti-Brain-derived neurotrophic factor (BDNF) chicken polyclonal primary antibody detects human and mouse Brain-derived neurotrophic factor (BDNF), and is IgY. It is validated for use in ELISA.

Brain-derived neurotrophic factor; Abrineurin; proBDNF

P23560

Human and Mouse

Mixture of two human BDNF peptides (73-87 and 194-208 aa) . Both peptides are highly conserved in human and mouse.

Brain-derived neurotrophic factor (BDNF)

Unconjugated

ELISA

Technical Note #4 - Acid-Extraction of BDNF From Brain Tissue Instructions for Acid-Extraction of Brain Tissue BDNF Antibodies for Western Blotting

IgY

PBS with 0.02% Sodium Azide

For research use only.

2-8°C (on cold packs)

Short term storage at 2-8°C for one week. At -20°C as an undiluted liquid for up to 12 months.

Mammalian BDNF.

Chicken

Liquid

IgY

Human