Anti-BSEP Monoklonale Antilichaam (Kloon:IHC518)

Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, which mediates the transport of bile acid, taurocholate and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2) . PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life

ABCB11||BSEP

ABCB11

8647

O95342

Human

Recombinant Human BSEP

IHC518

IHC

Protein A/G Chromatography

Purified

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and

Store at 2°C - 8°C. Do not freeze.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

Mouse IgG1