Anti-c-Rel Monoklonale Antilichaam

Boster Bio Anti-c-Rel Monoclonal Antibody catalog # M01880. Tested in WB, IP applications. This antibody reacts with Human.

Adiponectin receptor protein 1; Progestin and adipoQ receptor family member I; ADIPOR1; PAQR1 , TESBP1A; CGI-45

REL

5966

Q04864

Human

A synthesized peptide derived from human c-Rel c-Rel contains an amino-terminal DNA-binding domain referred to as the REL homology domain (REH) and carboxy-terminal transactivation domains. The c-Rel protein is typically inhibited in unstimulated cells by I Kappa B Alpha and I Kappa B Beta . c-Rel expression is highest in hematopoietic cells with extensive research studies demonstrating its role in immune cell function and pathogenesis of disease.

Clone: ADDH-18

Widely expressed (PubMed:16044242) . Highly expressed in heart and skeletal muscle (PubMed:12802337) . Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337) . Weakly expressed in colon, thymus and small intestine (PubMed:12802337) . .

WB, IP

Transcription Factors

Affinity-chromatography

0.5mg/ml

Liquid

Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337) . Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01880

42616 MW

78 kDa

Adiponectin receptor protein 1

Cell membrane ; Multi-pass membrane protein . Localized to the cell membrane and intracellular organelles. .

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.