Anti-C-X-C motief chemokine 16 CXCL16 Antibody Picoband®

CXCL16, Chemokine (C-X-C motif) ligand 16, is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids), CXCL16 is composed of a CXC chemokine domain, a mucin-like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2. By somatic cell hybrid analysis, the CXCL16 gene is mapped to 17p13, a locus separate from all other known chemokines. Chemotaxis assays found that CXCL16 induced a strong chemotactic response in activated CD8 T cells. In addition, CXCL16 induced calcium mobilization.

Boster Bio Anti-C-X-C motif chemokine 16 CXCL16 Antibody catalog # PA1460. Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

C-X-C motif chemokine 16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine CXCL16; Cxcl16; Srpsox

CXCL16

66102

Q8BSU2

Mouse

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence in the middle region of mouse CXCL16.

Widely expressed. Not detected in purified B- and T-cells. .

IHC, WB

Chemokines, Immunology, Innate Immunity, Macrophage/Inflammation

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. .

1. Matloubian, M., David, A., Engel, S., Ryan, J. E., Cyster, J. G.A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.Nature Immun. 1: 298-304, 2000. 2. Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Kataoka, H., Kita, T., Yonehara, S.Molecular cloning of a novel scavenger receptor for oxidized low absorbance lipoprotein, SR-PSOX, on macrophages.J. Biol. Chem. 275: 40663-40666, 2000. 3. Wilbanks, A., Zondlo, S. C., Murphy, K., Mak, S., Soler, D., Langdon, P., Andrew, D. P., Wu, L., Briskin, M.Expression cloning of the STRL33/BONZO/TYMSTR ligand reveals elements of CC, CXC, CX3C chemokines.J. Immun. 166: 5145-5154, 2001.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=PA1460

26896 MW

26-35 kDa

No cross reactivity with other proteins.

C-X-C motif chemokine 16

Membrane ; Single-pass type I membrane protein .

Belongs to the SFTPA family.

C-X-C motif chemokine 16

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2mg Na2HPO4.