Anti-C14orf166/RTraf Antilichaam Picoband® APC-vervoeging

Enables RNA binding activity; RNA polymerase II complex binding activity; and identical protein binding activity. Involved in negative regulation of protein kinase activity; positive regulation of transcription by RNA polymerase II; and tRNA splicing, via endonucleolytic cleavage and ligation. Located in microtubule cytoskeleton; nucleoplasm; and perinuclear region of cytoplasm. Part of tRNA-splicing ligase complex.

RTRAF; C14orf166; CGI-99; RNA transcription, translation and transport factor protein; CLE7 homolog; CLE; hCLE

RTRAF

51637

Q9Y224

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human C14orf166/RTRAF recombinant protein (Position: M1-R244) . Human C14orf166/RTRAF shares 97.1% amino acid (aa) sequence identity with mouse C14orf166/RTRAF.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/18/2014. 2. Howng, S.-L., Hsu, H.-C., Cheng, T.-S., Lee, Y.-L., Chang, L.-K., Lu, P.-J., Hong, Y.-R. A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3-beta and is highly expressed in brain tumors. FEBS Lett. 566: 162-168, 2004. 3. Huarte, M., Sanz-Ezquerro, J. J., Roncal, F., Ortin, J., Nieto, A. PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators. J. Virol. 75: 8597-8604, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

28 kDa

6

RNA transcription, translation and transport factor

RNA transcription, translation and transport factor protein

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.