Anti-Calbindin/CALB1 Antibody Picoband®

Calbindin is a calcium-binding protein belonging to the troponin C superfamily. Calretinin is expressed in central and peripheral nervous system and in many normal and pathological tissues. The rat and human calretinin exhibit 98% sequence homology and 91% homology to many other species. Two calcium binding proteins, calbindin and calretinin, have been reported to be expressed in abundance in Purkinje cells and other cell types in the cerebellum.

Boster Bio Anti-Calbindin/CALB1 Antibody Picoband® catalog # PB9045. Tested in IP, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Calbindin; Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type; CALB1; CAB27

CALB1

793

P05937

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human Calbindin recombinant protein (Position: A2-E175) . Human Calbindin shares 99% amino acid (aa) sequence identity with both mouse and rat Calbindin.

Expressed in all cell types so far analyzed.

IP, IHC, WB

Calcium Binding Proteins, Calcium Signaling, Cell Type Marker, Neuron Marker, Neuroscience, Neurotransmission

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Buffers cytosolic calcium. May stimulate a membrane Ca (2+) -ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

1. Parmentier M.; The human calbindins: cDNA and gene cloning.; Adv. Exp. Med. Biol. 255:233-240 (1989) . 2. Strauss K.I., Kuznicki J., Winsky L., Kawagoe J.I., Hammer M., Jacobowitz D.M.; The mouse calretinin gene promoter region: structural and functional components.; Brain Res. Mol. Brain Res. 49:175-187 (1997) . 3. Gabrielides C., McCormack A.L., Hunt D.F., Christakos S.; Brain calbindin-D28k and an Mr 29,000 calcium binding protein in cerebellum are different but related proteins: evidence obtained from sequence analysis by tandem mass spectrometry.; Biochemistry 30:656-662 (1991) .

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=PB9045

30 kDa

36 kDa

No cross reactivity with other proteins.

Calbindin

Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Localizes within both nucleus and cytoplasm of proliferative primary myoblasts and mostly within the nucleus of differentiated primary myoblasts. By virtue of the N-terminal PH domain, is recruited to sites of the plasma membrane containing increased PI (3,4,5) P3 or PI (3,4) P2, cell membrane targeting is also facilitared by interaction with CLIP3.

Belongs to the calbindin family.

Calbindin

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.