Anti-Calponine 3/CNN3 Antibody Picoband® fluoro647 Vervoeging

Calponin 3. acidic is a protein that in humans is encoded by the CNN3 gene. This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction.

Neuropeptides B/W receptor type 1; G-protein coupled receptor 7; NPBWR1; GPR7

CNN3

1266

Q15417

Human, Rat

No cross-reactivity with other proteins.

A synthetic peptide corresponding to a sequence at the C-terminus of human Calponin 3/CNN3, identical to the related mouse and rat sequences.

Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.

Flow Cytometry

Immune System Diseases, Immunology, Protein Trafficking, Signal Transduction, Signaling Pathway

Immunogen affinity purified.

Liquid

Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.

1. Maguchi, M., Nishida, W., Kohara, K., Kuwano, A., Kondo, I., Hiwada, K. Molecular cloning and gene mapping of human basic and acidic calponins. Biochem. Biophys. Res. Commun. 217: 238-244, 1995.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Neuropeptides B and W receptor 1

Cell membrane. Multi-pass membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.