Anti-Calponine Cnn2 Antilichaam (Monoclonal, CP-93)

Calponin is a basic 34-kD protein first isolated from chicken gizzard and bovine aorta. It is specifically expressed in smooth muscle and binds calmodulin, actin, and tropomyosin. It is able to inhibit the ATPase activity of myosin and is though to play a role in smooth muscle contraction. Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein though to be involved in some way in the regulation or modulation of contraction.

Boster Bio Anti-Calponin Cnn2 Antibody (Monoclonal, CP-93) catalog # MA1011. Tested in IHC, ICC, WB applications. This antibody reacts with Chicken, Human, Turkey.

Calponin-2; Calponin H2, smooth muscle; Neutral calponin; Cnn2

CNN2

Human (1265), Mouse (12798)

Q08093

Chicken, Human, Turkey

No cross-reactivity with other proteins

Turkey gizzard calponin

Clone: CP-93

Smooth muscle, and tissues containing significant amounts of smooth muscle.

IHC, ICC, WB

Actin Binding Proteins, Actin, etc., Cardiovascular, Contractility, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Ascites

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Lyophilized

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

1. Strasser, P.; Gimona, M.; Moessler, H.; Herzog, M.; Small, J. V. : Mammalian calponin: identification and expression of genetic variants. FEBS Lett. 330: 13-18, 1993.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=MA1011

33156 MW

33 kDa

No cross reactivity with other proteins.

Calponin-2

Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules. .

Belongs to the calponin family.

Calponin-2

Mouse IgG1

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.