Anti-caspase-3 (p17 subunit) Antilichaam

The caspases are a group of cysteine enzymes, which cleave proteins in response to intrinsic and extrinsic pathways that cause apoptotic cell death. The caspases can be grouped into two subgroups based on their roles in apoptosis. Initiator caspases (caspases 2, 8, 9, and 10) are activated through the apoptosis-signaling pathways and activate the effector caspases (caspases 3, 6, and 7) which carry out apoptosis. Caspase cascades are initiated through assembly of multiprotein complexes that trigger activation of the initiator caspases, which are then released and are able to activate the downstream effector caspases.

Our Caspase-3 (p17 subunit) primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, mouse, and rat Caspase-3 (p17 subunit) and is protein g purified. It is great for use in ELISA, WB, IHC.

Our Caspase-3 (p17 subunit) primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, mouse, and rat Caspase-3 (p17 subunit) and is Protein G purified. It is great for use in WB, IHC.

Yama, CPP32, apopain, CASP3

CASP3

P42574

Human, Mouse, and Rat

Clone 31A1067 was developed against full-length recombinant human Caspase-3. The antibody recognizes an epitope in the large domain subunit (p17) of Caspase-3, and it will recognize pro Caspase-3 and the p17 cleavage fragment.

Caspase-3 (p17 subunit)

31A1067

Unconjugated

ELISA, WB, IHC

Apoptosis, Cell Signaling

Protein G Purified

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

32

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Blue Ice

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Protein G purified culture supernatant.

1:250

The antibody detects pro Caspase-3 at 32 kDa* and the large subunit of the cleaved form of Caspase-3 at 14-21 kDa. The antibody can be used for western blot, immunohistochemistry and immuno-electron microscopy.

Western blots performed on each lot.

Mouse

Liquid

IgG1

Human

Quality Control: WB

AB_3068396