Anti-Caspase-8 (C-terminaal gebied) Antilichaam

The caspases are a group of cysteine enzymes, which cleave proteins in response to intrinsic and extrinsic pathways that cause apoptotic cell death. The caspases can be grouped into two subgroups based on their roles in apoptosis. Initiator caspases (caspases 2, 8, 9, and 10) are activated through the apoptosis-signaling pathways and activate the effector caspases (caspases 3, 6, and 7) which carry out apoptosis. Caspase cascades are initiated through assembly of multiprotein complexes that trigger activation of the initiator caspases, which are then released and are able to activate the downstream effector caspases.

Our Caspase-8 (C-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects human Caspase-8 (C-terminal region) and is protein a purified. It is great for use in ELISA, WB.

Our Caspase-8 (C-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects human Caspase-8 (C-terminal region) and is Protein A purified. It is great for use in WB.

Caspase-8, ced3, NEDD2-like protein, p15, p10

CASP8

Q14790

Human

Clone (M382) was generated from a recombinant protein containing amino acid residues in the C-terminal region of human Caspase-8.

Caspase-8 (C-terminal region)

M382

Unconjugated

ELISA, WB

Apoptosis, Cell Signaling

Protein A Purified

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

55

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Blue Ice

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Protein A purified culture supernatant.

1:500

The antibody detects a 55 kDa* protein corresponding to the molecular weight of Caspase-8 on SDS-PAGE immunoblots of human Jurkat, K562, and A431 cells.

Western blots performed on each lot.

Mouse

Liquid

IgG2a

Human

Quality Control: WB

AB_1944431