Anti-CAT1/SLC7A1 Antibody Picoband® fluoro488 Vervoeging

High affinity cationic amino acid transporter 1, also called solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (SLC7A1) or ATRC1 is a protein that in humans is encoded by the SLC7A1 gene. This gene is mapped to 13q12.3. It acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor and plays a role in the Na+-independent y+ cationic amino acid transport system. This gene is high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues.

High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor homolog; Ecotropic retrovirus receptor homolog; ERR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter; SLC7A1; ATRC1, ERR, REC1L

SLC7A1

6541

P30825

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human CAT1, different from the related mouse and rat sequences by four amino acids.

Ubiquitous. .

Flow Cytometry

Channels, Metabolism, Plasma Membrane, Signal Transduction

Immunogen affinity purified.

Liquid

High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. May also function as an ecotropic retroviral leukemia receptor. .

1. Bhattacharyya, S. N., Habermacher, R., Martine, U., Closs, E. I., Filipowicz, W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125: 1111-1124, 2006. 2. Bowcock, A. M., Gerken, S. C., Barnes, R. I., Shiang, R., Jabs, E. W., Warren, A. C., Antonarakis, S., Retief, A. E., Vergnaud, G., Leppert, M., Lalouel, J.-M., White, R. L., Cavalli-Sforza, L. L. The CEPH consortium linkage map of human chromosome 13. Genomics 16: 486-496, 1993. 3. Kozak, C. A., Albritton, L. M., Cunningham, J. M. Genetic mapping of a cloned sequence responsible for susceptibility to ecotropic murine leukemia viruses. J. Virol. 64: 3119-3121, 1990.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

67638 MW

No cross reactivity with other proteins.

6

High affinity cationic amino acid transporter 1

Cell membrane ; Multi-pass membrane protein .

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

High affinity cationic amino acid transporter 1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.