Anti-Cathepsin G/CSTS Antibody Picoband®
Gecertificeerd

Anti-Cathepsin G/CSTS Antibody Picoband®

Catalog #: PB9049
Maat: 100 µg/Vial

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. This gene is mapped to 14q12, human Cathepsin G gene was expressed in early myeloid precursors in a manner coordinate with the expression of the endogenous murine gene in the bone marrow and spleen. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation.

Description

Boster Bio Anti-Cathepsin G/CTSG Antibody Picoband® catalog # PB9049. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Synonyms

Cathepsin G; CG;3.4.21.20; CTSG

Gene Name

CTSG

Gene ID

1511

UniProt

P08311

Host

• Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human Cathepsin G recombinant protein (Position: A76-L255) . Human Cathepsin G shares 66% amino acid (aa) sequence identity with mouse Cathepsin G.

Clonality

• Polyclonal

Tissue Specificity

Expressed in the aorta extrcellular space (at protein level) . .

Applications

WB

Field of Research

Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. .

References & Citations

1. Entrez Gene: CTSG cathepsin G 2. Grisolano, J. L., Sclar, G. M., Ley, T. J. Early myeloid cell-specific expression of the human Casthepsin G gene in transgenic mice. Proc. Nat. Acad. Sci. 91: 8989-8993, 1994.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product MSDS

https://www.bosterbio.com/msds?sku=PB9049

Calculated Molecular Weight

28837 MW

Observed Molecular Weight

38 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Cathepsin G

Subcellular Location

Cell surface .

Sequence Similarities

Belongs to the peptidase S1 family.

Protein Name

Cathepsin G

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Beschrijving

Boster Bio Anti-Cathepsin G/CTSG Antibody Picoband® catalog # PB9049. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband in

Specificaties

ProductnaamAnti-Cathepsin G/CSTS Antibody Picoband®
Categorie
Beschikbare grootte100 µg/Vial
CatalogusnummerPB9049