Anti-Cathepsine G/CGTS Antibody Picoband® 0,00647 Vervoeging

Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. This gene is mapped to 14q12, human Cathepsin G gene was expressed in early myeloid precursors in a manner coordinate with the expression of the endogenous murine gene in the bone marrow and spleen. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation.

Cathepsin G; CG;3.4.21.20; CTSG

CTSG

1511

P08311

Human, Rat

No cross-reactivity with other proteins

E.coli-derived human Cathepsin G recombinant protein (Position: A76-L255) . Human Cathepsin G shares 66% amino acid (aa) sequence identity with mouse Cathepsin G.

Expressed in the aorta extrcellular space (at protein level) . .

Flow Cytometry

Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Immunogen affinity purified.

Liquid

Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. .

1. Entrez Gene: CTSG cathepsin G 2. Grisolano, J. L., Sclar, G. M., Ley, T. J. Early myeloid cell-specific expression of the human Casthepsin G gene in transgenic mice. Proc. Nat. Acad. Sci. 91: 8989-8993, 1994.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

28837 MW

No cross reactivity with other proteins.

6

Cathepsin G

Cell surface .

Belongs to the peptidase S1 family.

Cathepsin G

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.