Anti-Caveoline-1 Antilichaam

Caveolins are the primary structural components of the plasma membrane microdomains, caveolae. Three members of the caveolin family (caveolin-1, -2, and -3) have been identified, and each has distinct expression patterns. Caveolins are involved in diverse biological functions, including vesicular trafficking, cholesterol homeostasis, cell adhesion and apoptosis. Caveolins can interact with various signaling molecules, including G-proteins, receptor tyrosine kinases, PKCs, and Src family kinases. Phosphorylation at Tyr-14 is essential for caveolin association with SH2 or PTB domain-containing adaptor proteins, while phosphorylation at Ser-80 regulates caveolin binding to the ER membrane and entry into the secretory pathway.

Our Caveolin-1 primary antibody from PhosphoSolutions is mouse monoclonal. It detects chicken, human, mouse, and rat Caveolin-1 and is protein a purified. It is great for use in ELISA, WB, ICC.

Our Caveolin-1 primary antibody from PhosphoSolutions is mouse monoclonal. It detects chicken, human, mouse, and rat Caveolin-1 and is Protein A purified. It is great for use in WB, ICC.

Caveolin1, vip21

CAV1

Q03135

Chicken, Human, Mouse, and Rat

Clone (M281) was generated from a full length recombinant human Caveolin-1 protein.

Caveolin-1

M281

Unconjugated

ELISA, WB, ICC

Cardiovascular, Oncoproteins

Protein A Purified

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

GOmAb

21

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Blue Ice

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Protein A purified culture supernatant.

1:500

This antibody detects a 21 kDa* protein corresponding to the apparent molecular mass of caveolin-1 on SDS-PAGE immunoblots of human A431 cells and rabbit spleen fibroblasts.

1:50

Western blots performed on each lot.

Mouse

Liquid

IgG1

Human

Quality Control: WB

AB_2072010