Anti-CBFb Konijn Monoklonale Antilichaam

Boster Bio Anti-CBFb Rabbit Monoclonal Antibody catalog # M01007-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

TAR DNA-binding protein 43; TDP-43; TARDBP; TDP43

CBFB

865

Q13951

Human, Mouse, Rat

A synthesized peptide derived from human CBFb

Clone: 20C03

Ubiquitously expressed. In particular, expression is high in pancreas, placenta, lung, genital tract and spleen.

WB, IHC, ICC, IF, Flow Cytometry

Neuropeptides, Neuroscience, Neurotransmitter

Affinity-chromatography

0.5mg/ml

Liquid

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a interaction with the 3' UTR. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01007-1

44740 MW

22 kDa

TAR DNA-binding protein 43

Nucleus . In patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis, it is absent from the nucleus of affected neurons but it is the primary component of cytoplasmic ubiquitin-positive inclusion bodies.

Glycogen synthase kinase-3 beta (gsk3b)

IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.