Anti-CBP20/NCBP2 Antibody Picoband® fluoro594 Vervoeging

The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.

BMP and activin membrane-bound inhibitor homolog; Non-metastatic gene A protein; Putative transmembrane protein; NMA; BAMBI; NMA

NCBP2

22916

P52298

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human CBP20/NCBP2 recombinant protein (Position: S2-N102) .

Expressed in adult liver.

Flow Cytometry

Atherosclerosis, Cardiovascular, Chaperones, Heat Shock Proteins, Protein Trafficking, Signal Transduction

Immunogen affinity purified.

Liquid

Negatively regulates TGF-beta signaling.

1. Gebhardt, A., Habjan, M., Benda, C., Meiler, A., Haas, D. A., Hein, M. Y., Mann, A., Mann, M., Habermann, B., Pichlmair, A. mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. Nature Commun. 6: 8192, 2015. Note: Electronic Article. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 10/28/2015. 3. Izaurralde, E., Lewis, J., Gamberi, C., Jarmolowski, A., McGuigan, C., Mattaj, I. W. A cap-binding protein complex mediating U snRNA export. Nature 376: 709-712, 1995.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

17136 MW

6

BMP and activin membrane bound inhibitor

Cytoplasm . Nucleus . Translocates to nuclear foci during heat shock.

Chromaffin granule amine transporter

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.